- The number of Pokemon you can catch is 649, plus some more from Gen VI.
- No waiting to get running shoes. You get to run at the start of the freaking game. Why do you need special shoes to run? Also can run indoors.
- HMs are removed.
- To use the first HM Rock Smash, you only need to have your starter in the party.
- Some movesets are updated to the Pokemon Black 2/White 2 or Pokemon X/Y.